الأبحاث العلمية المنشورة

1.  Al Doghaither, H.A., Elmorsy, E., Al-Ghafari, A.B., Ghulam, J.M. (2020) Roles of oxidative stress, apoptosis, and inflammation in metal-induced dysfunction of beta pancreatic cells isolated from CD-1 mice. Saudi Journal of Biological Sciences, in progress.

2. Elmorsy, E., Al-Ghafari, A.B., Al Doghaither, H.A., Ghulam, J.M. (2020) Effects of environmental heavy metals on mitochondrial bioenergetics of the CD-1 pancreatic ꞵ-cells of mice. Toxicology in vitro, in progress.

3.   Bakhrebah, M., Nasrullah, M., Abdulaal, W.H., Hassan, M., Siddiqui, H., Al Doghaither, H.A., Omar, U.M., Helmi, N., Fallatah, M.M., Al-Ghafari, A.B., Khan, M.I., Choudhry, H. (2020) High expression of PD-1 in circulating cells of patients with advanced colorectal cancer receiving adjuvant therapy. Technology in Cancer Research & Treatment, in progress.

4. Al-Ghafari, A.B., Siddiqui, H.A., Choudhry, H.M., Al Doghaither, H.A., Elmorsy, E.A., Alshaibi, H.F., Alsufiani, H.M. (2020) The contribution of long non-coding RNAs (CCAT1, MALAT1, and PANDAR) in the pathogenesis of colorectal cancer. Pakistan Journal of Medical Sciences, in progress.

5. Al-Ghafari, A., Alqahtani, A., Alturki, S., Elmorsy, E., Al Doghaither, H., Tashkandi, H., Abusanad, A., Alkhayyat, S., Zeeneldin, A. (2020) MDR1 polymorphisms are not related to XELIRI and XELOX chemoresistance in colorectal cancer. Oncology Letters, 20:155.

6. Alelwani, W., Elmorsy, E., Kattan, S.W., Babteen, N.A-B., Alnajeebi, A.M., Al-Ghafari, A., Carter, W.G. (2020) Carbamazepine induces a bioenergetics disruption to microvascular endothelial cells from the blood-brain barrier. Toxicology Letters, 333:184-191.

7. Qutub, R.M., Al-Ghafari, A.B., Al Doghaither, H.A., Omar, U.M., Ghulam, J.M. (2020) Increased expressions of ATP-binding cassette transporters may be a promising diagnostic marker for colorectal cancer. Saudi Medical Journal, 41(8): 834-840.

8.  Al-Ghafari, A.B., Balamash, K.S., Al Doghaither, H.A. (2020) TaqI and ApaI variants of the vitamin D receptor gene increase the risk of colorectal cancer in a Saudi population. Saudi Journal of Medicine and Medical Sciences, 8:188-195.

9.  Banjabi, A.A., Al-Ghafari, A.B., Kumosani, T.A., Kannan, K., Fallatah, S.M. (2020) Genetic influence of vitamin D receptor gene polymorphisms on osteoporosis risk. International Journal of Health Sciences (Qassim), 14(4): 22-28.

10. Kuerban, A-K., Al-Ghafari, A.B., AlGhamadi, S.A., Syed, F.Q., Mirza, M.B., Mohammed, F.A., Abulnaja, K.O., Alshaibi, H.F., Alsufiani, H.M., Kumosani, T.A., Al-Malki, A.L., Moselhy, S.S. (2020) Potential antiglycation, antioxidant and antiproliferative activities of Vicia faba peptides. Journal of Food Measurement and Characterization, DOI: https://doi.org/10.1007/s11694-020-00462-9.

11. Balkhair, A.M., Al-Ghafari, A., Tashkandi, H., Alturki, S., Al Doghaither, H., Abusanad, A., Alkhayyat, S., Yezerski, A., Zeeneldin, A. (2020) Contribution of ABCG2 gene polymorphisms (G34A and C376T) in the prognosis of colorectal cancer. Indian Journal of Biochemistry and Biophysics, 57:73-78.

12. Al-Ghafari, A.B., Balamash, K.S., Al Doghaither, H.A. (2020) Serum vitamin D receptor (VDR) levels as a potential diagnostic marker for colorectal cancer. Saudi Journal of Biological Sciences, 27(3):827-832.

13. Alharbi, M.F., Al-Ghafari, A.B., Al Doghaither, H.A., Alshaibi, H.F., Omar, U.M. (2020) Contribution of apolipoprotein E isoforms to colorectal cancer carcinogenesis. Pakistan Journal of Biological Sciences, 23: 306-312.

14. Al-Sahafi, M.A., Al-Ghafari, A.B., Al Doghaither, H.A., Omar, U.M., Abusanad, A.M., Khayyat, S.S., Elmorsy, E.A., Tashkandi, H.M. (2020) Serum levels of Apolipoprotein E in colorectal cancer patients and its relationship with the diagnosis of the disease. Annals of Clinical and Analytical Medicine, DOI:10.4328/ ACAM.20092.

15.  Elmorsy, E.M., Parrey, M., Al-Ghafari, A. (2019) Lead-induced bioenergetics disruption and oxidative stress in the cultured human retinal pigment epithelial cells. Pakistan Journal of Medical and Health Sciences, 13(4): 1037-1041.

16.  Al-Ghafari, A., Elmorsy, E., Fikry, E., Alrowaili, M., Carter, W.G. (2019) The heavy metals lead and cadmium are cytotoxic to human bone osteoblasts via induction of redox stress. PLoS ONE, 14(11): e0225341.

17. Al Qahtani, A.M., Al-Ghafari, A.B., Al Doghaither, H.A., Alzahrani, A.H., Omar, U.M., Rahimulddin, S.A. (2019) ABCB1 variants C3435T and T129C are not associated with colorectal cancer risk. African Health Sciences, 19(3): 2476-2483.

18. Al Zahrani, S.M., Omar, U.M., Rahimulddin, S.A., Al-Ghafari, A.B., Aldahlawi, A.M., Al Doghaither, H.A. (2019) Antiproliferative and apoptotic effects of the natural alkaline water (Zamzam) in breast cancer cell line MCF-7. Journal of Cancer Research and Therapeutics, 15:1098-104.

19. Al-Ghafari, A., Balamash, K., Al Doghaither, H. (2019) Relationship between serum vitamin D and calcium levels and vitamin D receptor gene polymorphisms in colorectal cancer. BioMed Research International, 2019, article ID 8571541, 7 pages.

20. Siddique, H., Al-Ghafari, A., Choudhry, H., AlTurki, S., Alshaibi, H., Al Doghaither, H., Alsufiani, H. (2019) Long non-coding RNAs as prognostic markers for colorectal cancer in Saudi patients. Genetic Testing and Molecular Biomarkers, 23(8): 509-514.

21. Siddiqui, H., Al-Ghafari, A.B., Choudhry, H., Al Doghaither, H.A. (2019) Roles of long non-coding RNAs (lncRNAs) in colorectal cancer tumorigenesis. Molecular and Clinical Oncology, 11:167-172.

22. Al-Ghafari, A.B. (2019) Genetic variants of calcium sensing receptor gene and risk of colorectal cancer: A case-control study. Pakistan Journal of Medical Sciences, 35(2): 448-453.

23. Abdulkhaleq, M.M., Al-Ghafari, A.B., Yezerski, A., Al Doghaither, H.A., Abusanad, A.M., Omar, U.M. (2019) Novel association between heterozygous genotype of singly nucleotide polymorphism C218T in drug transporter ABCC1 gene and increased risk of colon cancer. Saudi Medical Journal, 40(3): 224-229.

24. Al Doghaither, H.A. and Al-Ghafari, A.B. (2018) Contribution of genetic variants of ATP transporters (ABCC1 and ABCG2) genes with the pathogenesis of colorectal cancer. Biosciences Biotechnology Research Asia, 15(3): 555-559.

25. Rasool, M., Malik, A., Ghuman, A.A., Ashraf, M.A., Arooj, M., Waquar, S., Zahid, S., Shaheen, S., Qazi, A., Naseer, M.I., Zamzami, M.A., Al-Ghafari, A., Baothman, O., Zeyadi, M., Helmi, N., Choudhry, H., Jamal, M.S., Al-Qahtani, M. (2018) Implications of isoprostanes and matrix metalloproteinase-7 having potential role in the development of colorectal cancer (CRC) in males. Frontiers in Oncology, 8:205.

26. Yea, G., Luoa, H., Rena, Z., Ahmad, M.S., Liuc, C.G., Abdul Tawabd, Al-Ghafari, A.B., Omar, U., Gull, M., Mehmood, M.A. (2018) Evaluating the bioenergy potential of Chinese liquor-industry waste through pyrolysis, thermogravimetric, kinetics and evolved gas analyses. Energy Conversion and Management, 163:13-21.

27. Kuerban, A., Yaghmoor, S.S., Almulaiky, Y.Q., Mohamed, Y.A., Razvi, S.S., Hasan, M.N., Moselhy, S.S., Al-Ghafari, A.B., Alsufiani, H.M., Kumosani, T.,  AL-Malki, A. (2017) Therapeutic effects of phytochemicals of Brassicaceae for management of obesity. Journal of Pharmaceutical Research International, 19(1):1-11.

28.  Elmorsy, E., Al-Ghafari, A., Almutairi, F., Aggour, A.M., Carter, W.G. (2017) Antidepressants are cytotoxic to rat primary blood brain barrier endothelial cells at high therapeutic concentrations. Toxicology in Vitro, 44: 154-163.

29.  Elmorsy, E., Al-Ghafari, A., Aggour, A.M., Khan, R., Amer, S. (2017) The role of oxidative stress in antipsychotics induced ovarian toxicity. Toxicology in Vitro, 44:190-195.

30. Kumosani, T.A., Iyer, A.P., Al-Ghafari, A.B., Zamzami, M.A. (2017) Association of telomerase activity with the prognosis of diabetes mellitus in Saudi population. Journal of Experimental Biology and Agricultural Sciences, 5(3): 277-281.

31. Elmorsy, E., Al-Ghafari, A., Helaly, A., Hisab, A.S., Oehrle, B., Smith, P.A. (2017) Therapeutic concentrations of antidepressants inhibit pancreatic beta-cell function via mitochondrial complex inhibition. Toxicological Sciences, 158(2): 286-301.

32. Omar, U.M., Al Doghaither, H.A., Rahimulddin, S.A., Al Zahrani, S.M., Al-Ghafari, A.B. (2017) In vitro cytotoxic and anticancer effects of Zamzam water in human lung cancer (A594) cell line. Malaysian Journal of Medical Sciences, 24(3):15–25.

33.  Elmorsy, E., Al-Ghafari, A., Aggour, A.M., Mosad, S.M., Khan, R., Amer, S. (2017) Effect of antipsychotics on mitochondrial bioenergetics of rat ovarian theca cells. Toxicology Letters, 272: 94-100.

34. Al-Ghafari, A.B., Alharbi, R.H., Al-Jehani, M.M., Bujeir, S.A., Al Doghaither, H.A., Omar, U.M. (2017) The effect of adding different concentrations of cows' milk on the antioxidant properties of coffee. Biosciences Biotechnology Research Asia, 14(1): 177-184.

35.  Al Doghaither, H.A., Alyousef, M.M., Al Selami, N.M., Al-Ghafari, A.B., Omar, U.M. (2017) Addition of evaporated milk alters the antioxidant properties of most commonly consumed coffee in Saudi Arabia. Malaysian Applied Biology, 46(2): 97-104.

36. Al-Ghafari, A.B. and Althaqafi, G.H. (2017) The effect of processing and roasting on the antioxidant activity of extracts from instant and ground coffee. Biosciences Biotechnology Research Asia, 14(1): 69-74.

37.  Al Doghaither, H.A., Almowalad, A.M., Shorbaji, A.M., Al-Ghafari, A.B., Omar, U.M. (2017) Assessment of the antioxidant properties of the most common coffee brews available in the local markets of the western region of Saudi Arabia. Journal of Experimental Biology and Agricultural Sciences, 5(1):070-076.

38. Elmorsy, E., Attalla, S.M., Al-Ghafari, A., Nwidu, L.L. (2016) Role of oxidative stress in antituberculous drugs (individuals and combined) cytotoxicity in HEPG2 cells. Malaysian Applied Biology, 45(2): 1-8.

39. Rahimulddin, S.A., Al-Ghafari, A.B., Omar, U.M., Al-Doghaither, H.A., Al Zahrani, S.M. (2016) Influence of pH and sterilization conditions on the inhibitory effects of Zamzam water on the cell viability of cancer cells. Journal of Biological Sciences, 16(6): 229-235.

40. Al-Doghaither, H.A., Omar, U.M., Rahimulddin, S.A., Al-Ghafari, A.B. (2016) Cytotoxic effects of aqueous extracts of Urtica Urens on most common cancer types in Saudi Arabia. Journal of Biological Sciences, 16(6): 242-246.

41. Al-Doghaither, H.A., Al-Ghafari, A.B., Rahimulddin, S.A., Al-Zahrani, S.M., Omar A.M., Omar, U.M. (2016) Evaluation of the potential anticancer activity of Zamzam water in human colon cancer cell line. Cancer and Oncology research, 4(3): 33-41.

42. Omar, U.M., Shorbaji, A.M., Arrait, E.M., Al Agha, T.D., Al-Marzouki, H.F., Al Doghaither, H.A., Al-Ghafari, A.B. (2016) Comparative study of the antioxidant activity of two popular green tea beverages available in the local market of Saudi Arabia. Natural Science, 8(6): 227-234.

43. Al-Ghafari, A., Shorbaji, A., Al-Sarori, L., Baduwalian, E., Basaar, A., Al-Doghaither, H., Al-Marzouki, H., Omar, U. (2016) Phenolic Contents and Antioxidant activities of green tea with and without lemon. Natural Science, 8(6): 247-255.

44. Al-Ghafari, A., Punjaruk, W., Storer, L., Carrier, D., Hussein, D., Coyle, B. and Kerr, I. (2016) Long-term exposure to irinotecan reduces cell migration in glioma cells. Journal of Neuro-oncology, 127(3): 455-462.

45. Al-Harithy, R. and Al-Ghafari, A. (2014) Influence of combined genotypes of RETN G62A with C-180G and G299A polymorphisms on colon cancer risk. Cancer Biology, 4(2): 79-86.

46. Al-Ghafari, A., Punjaruk, W., Coyle, B., and Kerr, I. (2012) Abstract from the 15th International Symposium on Pediatric Neuro-Oncology, June 24-27 2012 Toronto, Ontario, Canada. Journal of Neuro-oncology, volume 14, supplementary 1.

47. Al-Harithy, R. and Al-Ghafari, A. (2010) Resistin in Human Colon Cancer: Increased expression independently of resistin promoter C-180G genotype. Saudi Medical Journal, 31(5): 495-500.


آخر تحديث
10/5/2020 12:49:58 PM